Early detection of sepsis in healthcare is an invaluable capability for professionals in any care setting. Quickly identifying sepsis can save lives, but until now, there’s been no reliable tool to recognize the condition or explore alternate diagnoses, explained Hollis O’Neal, MD, Critical Care physician at LSUHSC and Medical Director of Research at Our Lady of the Lake Regional Medical Center. Dr. O’Neal led the national investigation that resulted in the novel “IntelliSep” test, which was recently cleared by the FDA.

What is Sepsis? Sepsis is a dysregulated, systemic inflammatory response to infection that causes tissue damage, organ failure, and, in severe cases, can lead to death. Anyone can develop sepsis, but older adults and those with significant comorbidities, weakened immune systems, or chronic conditions like cancer, chronic lung disease, and heart failure are particularly at risk. Early detection of sepsis in healthcare and timely, guideline-based interventions are linked to lower in-hospital mortality rates.

The IntelliSep test examines blood samples from patients as they enter the emergency room to determine whether white blood cells exhibit patterns indicating sepsis. In under 10 minutes, this test provides results, equipping emergency department teams for time-sensitive decisions that can be lifesaving. Similar to lactic acid testing in the ER, the IntelliSep test is unlikely to be available in post-acute care anytime soon. Our responsibility remains to recognize sepsis when we see it and to act quickly and effectively. Numerous educational resources are available to train staff on the signs of sepsis, and the “Surviving Sepsis Campaign” guidelines are essential for treatment protocols.

Remember, sepsis is deadly. Don’t wait, don’t hesitate; when in doubt, send them out!

Stay well and stay informed!